NOX4 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-70215-60uL | 60uL | £184.00 |
Quantity:
| E-AB-70215-120uL | 120uL | £251.00 |
Quantity:
| E-AB-70215-200uL | 200uL | £351.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
NOX4
Background:
This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Calculated MW:
70kDa
Concentration:
0.9 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:2000, IHC 1:400-1:1000
Immunogen:
KLH conjugated Synthetic peptide corresponding to Mouse NOX4
ObservedMW:
70kDa
Purification method:
Affinity purification
Target Synonym:
Kidney oxidase 1;Kidney oxidase-1;Kidney superoxide producing NADPH oxidase;Kidney superoxide-producing NADPH oxidase;KOX 1;KOX;Kox-1;KOX1;NADPH;NADPH oxidase 4;Nox4;NOX4;Renal NAD(P)H oxidase;Renal NAD(P)H-oxidase;RENOX
UNIProt ID:
Q9NPH5,Q9JHI8,Q924V1