NFAT2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-60332-60uL | 60uL | £210.00 |
Quantity:
| E-AB-60332-120uL | 120uL | £291.00 |
Quantity:
| E-AB-60332-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
NFAT2
Background:
The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
38kDa/74- 88kDa/100-101kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:3000 IHC 1:50-1:200
Immunogen:
Recombinant fusion protein of human NFAT2 (NP_765978.1).
ObservedMW:
78kDa
Purification method:
Affinity purification
Target Synonym:
NF-ATC;NF-ATc1.2;NFAT2;NFATc;NFATC1
UNIProt ID:
O95644