NF2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-61787-60uL | 60uL | £210.00 |
Quantity:
| E-AB-61787-120uL | 120uL | £291.00 |
Quantity:
| E-AB-61787-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
NF2
Background:
This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development; in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts.
Buffer:
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Calculated MW:
19-30kDa/59-72kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human NF2
ObservedMW:
73KDa
Purification method:
Affinity purification
Target Synonym:
NF2;ACN;BANF;SCH;merlin
UNIProt ID:
P35240