N-cadherin Polyclonal Antibody

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Elabscience
Product Code: E-AB-70061
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-70061-60uL60uL£184.00
Quantity:
E-AB-70061-120uL120uL£251.00
Quantity:
E-AB-70061-200uL200uL£351.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunohistochemistry analysis of paraffin-embedded human liver using N-cadherin Polyclonal Antibody at dilution of 1:500.
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Immunohistochemistry analysis of paraffin-embedded human liver using N-cadherin Polyclonal Antibody at dilution of 1:500.

Documents

Further Information

Abbreviation:
N-cadherin
Background:
Cadherins are a family of transmembrane glycoproteins that mediate calcium-dependent cell-cell adhesion and play an important role in the maintenance of normal tissue architecture. N-cadherin (neural cadherin),also known as CDH2 (cadherin 2),is a classical member of the cadherin superfamily which also include E-,P-,R-,and B-cadherins. Expression of N-cadherin has been reported on various cell types including neurons,endothelial cells and cardiac myocytes . N-cadherin has functions in early brain morphogenesis,synaptogenesis and synaptic plasticity .
Buffer:
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Calculated MW:
100/120/140kDa
Concentration:
200 ug/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:300-1:800
Immunogen:
KLH conjugated Synthetic peptide corresponding to Mouse N-cadherin
ObservedMW:
120kDa
Purification method:
Affinity purification
Target Synonym:
CADH2;Cadherin 2;Cadherin 2 N cadherin neuronal;Cadherin 2 type 1;Cadherin 2 type 1 N cadherin neuronal;Cadherin 2;type 1;N-cadherin (neuronal);Cadherin-2;Cadherin2;Calcium dependent adhesion protein neuronal;CD325;CD325 antigen;CDH2;CDHN;CDw325;CDw325 antigen;N cadherin 1;N-cadherin;NCAD;Neural cadherin;OTTHUMP00000066304;OTTHUMP00000067378
UNIProt ID:
P19022,P15116,Q9Z1Y3

References

  • https://www.sciencedirect.com/science/article/pii/S1385894721041012
  • https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-021-01198-4
  • https://cellandbioscience.biomedcentral.com/articles/10.1186/s13578-023-00963-2
  • https://www.mdpi.com/2055064
  • https://www.mdpi.com/1660-3397/20/10/595
  • https://www.ncbi.nlm.nih.gov/pmc/articles/pmc8187004/
  • https://portlandpress.com/biochemj/article-abstract/doi/10.1042/BCJ20210830/231374
  • https://onlinelibrary.wiley.com/doi/abs/10.1002/mc.23264
  • https://www.ncbi.nlm.nih.gov/pmc/articles/pmc8607078/