MYO5A Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-62133-60uL | 60uL | £210.00 |
Quantity:
| E-AB-62133-120uL | 120uL | £291.00 |
Quantity:
| E-AB-62133-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunofluorescence (IF)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
MYO5A
Background:
This gene is one of three myosin V heavy-chain genes, belonging to the myosin gene superfamily. Myosin V is a class of actin-based motor proteins involved in cytoplasmic vesicle transport and anchorage, spindle-pole alignment and mRNA translocation. The protein encoded by this gene is abundant in melanocytes and nerve cells. Mutations in this gene cause Griscelli syndrome type-1 (GS1), Griscelli syndrome type-3 (GS3) and neuroectodermal melanolysosomal disease, or Elejalde disease. Multiple alternatively spliced transcript variants encoding different isoforms have been reported, but the full-length nature of some variants has not been determined.
Buffer:
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Calculated MW:
212kDa/215kDa/218kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000,IF 1:50-1:100
Immunogen:
Recombinant fusion protein of human MYO5A
ObservedMW:
240kDa
Purification method:
Affinity purification
Target Synonym:
MYO5A;GS1;MYH12;MYO5;MYR12;myosin VA
UNIProt ID:
Q9Y4I1
References
- https://www.sciencedirect.com/science/article/pii/S0003986120303805