MTHFD1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-65595-60uL | 60uL | £210.00 |
Quantity:
| E-AB-65595-120uL | 120uL | £291.00 |
Quantity:
| E-AB-65595-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunofluorescence (IF)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
MTHFD1
Background:
This gene encodes a protein that possesses three distinct enzymatic activities, 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase. Each of these activities catalyzes one of three sequential reactions in the interconversion of 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine, thymidylate, and de novo purine syntheses. The trifunctional enzymatic activities are conferred by two major domains, an aminoterminal portion containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
101kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:200-1:2000 IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human MTHFD1 (NP_005947.3).
ObservedMW:
115kDa
Purification method:
Affinity purification
Target Synonym:
MTHFD1;MTHFC;MTHFD
UNIProt ID:
P11586