MMP13 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-70346-60uL | 60uL | £184.00 |
Quantity:
| E-AB-70346-120uL | 120uL | £251.00 |
Quantity:
| E-AB-70346-200uL | 200uL | £351.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
MMP13
Background:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Buffer:
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Calculated MW:
54kDa
Concentration:
0.55 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
KLH conjugated Synthetic peptide corresponding to Mouse MMP13
ObservedMW:
54kDa
Purification method:
Affinity purification
Target Synonym:
CLG 3;CLG3;Collagenase 3;Collagenase3;MANDP1;Matrix metallopeptidase 13 (collagenase 3);Matrix Metalloproteinase 13;Matrix metalloproteinase-13;MMP 13;MMP-13;Mmp13;MMP13
UNIProt ID:
P45452,P33435
References
- https://www.sciencedirect.com/science/article/pii/S0024320519309026
- https://www.sciencedirect.com/science/article/pii/S0753332219332202