MITF Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-60287-60uL | 60uL | £210.00 |
Quantity:
| E-AB-60287-120uL | 120uL | £291.00 |
Quantity:
| E-AB-60287-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
MITF
Background:
This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
40kDa/46kDa/52kDa/55kDa/56kDa/57kDa/58kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human MITF (NP_937801.1).
ObservedMW:
65kDa
Purification method:
Affinity purification
Target Synonym:
MITF;CMM8;COMMAD;MI;WS2;WS2A;bHLHe32
UNIProt ID:
O75030
References
- https://www.sciencedirect.com/science/article/pii/S0923181120302000