Mineralocorticoid receptor Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-70261-60uL | 60uL | £184.00 |
Quantity:
| E-AB-70261-120uL | 120uL | £251.00 |
Quantity:
| E-AB-70261-200uL | 200uL | £351.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
Mineralocorticoid receptor
Background:
This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Concentration:
1.3 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:200-1:800
Immunogen:
KLH conjugated Synthetic peptide corresponding to Mouse Mineralocorticoid receptor
Purification method:
Affinity purification
Target Synonym:
Aldosterone receptor;MCR;MGC133092;Mineralocorticoid receptor;MLR;MR;NR3 C2;NR3C2;NR3C2 protein;Nuclear receptor subfamily 3 group C member 2
UNIProt ID:
P08235,Q8VII8,P22199