METTL13 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-64259-60uL | 60uL | £210.00 |
Quantity:
| E-AB-64259-120uL | 120uL | £291.00 |
Quantity:
| E-AB-64259-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunofluorescence (IF)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
METTL13
Background:
Dual methyltransferase that catalyzes methylation of elongation factor 1-alpha (EEF1A1 and EEF1A2 at two different positions, and is therefore involved in the regulation of mRNA translation. Via its C-terminus, methylates EEF1A1 and EEF1A2 at the N-terminal residue 'Gly-2'. Via its N-terminus dimethylates EEF1A1 and EEF1A2 at residue 'Lys-55'. Has no activity towards core histones H2A, H2B, H3 and H4. Negatively regulates cell proliferation at G1/S transition via transcriptional suppression of cell cycle regulatory genes such as CDK4 and CDK6.
Buffer:
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Calculated MW:
44kDa/61kDa/68kDa/72kDa/78kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000,IF 1:50-1:100
Immunogen:
Recombinant fusion protein of human METTL13
ObservedMW:
85kDa
Purification method:
Affinity purification
Target Synonym:
METTL13;5630401D24Rik;CGI-01;KIAA0859;feat
UNIProt ID:
Q8N6R0