MCM7 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-40231-20uL | 20uL | £120.00 |
Quantity:
| E-AB-40231-60uL | 60uL | £160.00 |
Quantity:
| E-AB-40231-120uL | 120uL | £230.00 |
Quantity:
| E-AB-40231-200uL | 200uL | £331.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
MCM7
Background:
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Buffer:
PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Concentration:
2 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant Human DNA replication licensing factor MCM7 protien
Purification method:
Affinity purification
Target Synonym:
CDABP0042;CDC 47;CDC47;CDC47 homolog;Cdc47; S. cerevisiae; homolog of;DNA replication licensing factor MCM7;Homolog of S. cerevisiae Cdc47;MCM 2;MCM 7;MCM2;MCM2; formerly;Mcm7;MCM7 minichromosome maintenance deficient 7;MCM7_HUMAN;Minichromosome Maintainence 7;Minichromosome maintainence; S. cerevisiae; homolog of;Minichromosome maintenance complex component 7;Minichromosome maintenance deficient 7;Minichromosome maintenance protein 7;P1.1 MCM3;P1.1-MCM3;P1CDC47;P85MCM;PNAS 146;PNAS146;PPP1R104;Protein phosphatase 1; regulatory subunit 104
UNIProt ID:
P33993