MCM3 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-40230-20uL | 20uL | £120.00 |
Quantity:
| E-AB-40230-60uL | 60uL | £160.00 |
Quantity:
| E-AB-40230-120uL | 120uL | £230.00 |
Quantity:
| E-AB-40230-200uL | 200uL | £331.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
MCM3
Background:
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with mCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.05% Proclin300, 50% glycerol, pH7.3.
Calculated MW:
91,96 kDa
Concentration:
2mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:1000 IHC 1:50-1:200
Immunogen:
Recombinant Human DNA replication licensing factor MCM3 protein
ObservedMW:
100 kDa
Purification method:
Antigen Affinity Purification
Target Synonym:
Cervical cancer proto oncogene 5;DNA polymerase alpha holoenzyme associated P1;HCC 5;HCC5;hRlf beta subunit;Human cervical cancer proto oncogene 5;MCM 3;MGC1157;Minichromosome maintenance complex component 3;P1 h;P1 MCM3;P1.h;p102;Replication licensing factor beta subunit;
RLF beta subunit;RLFB
UNIProt ID:
P25205