MBNL1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-62123-60uL | 60uL | £210.00 |
Quantity:
| E-AB-62123-120uL | 120uL | £291.00 |
Quantity:
| E-AB-62123-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
MBNL1
Background:
This gene encodes a member of the muscleblind protein family which was initially described in Drosophila melanogaster. The encoded protein is a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Mice lacking this gene exhibited muscle abnormalities and cataracts. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. The different isoforms are thought to have different binding specificities and/or splicing activities.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
33kDa/34kDa/36kDa/37kDa/39kDa/40kDa/41kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:100
Immunogen:
Recombinant fusion protein of human MBNL1 (NP_066368.2).
ObservedMW:
42kDa
Purification method:
Affinity purification
Target Synonym:
MBNL1;EXP;MBNL
UNIProt ID:
Q9NR56