ZAK Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-65019-60uL | 60uL | £210.00 |
Quantity:
| E-AB-65019-120uL | 120uL | £291.00 |
Quantity:
| E-AB-65019-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Mouse
- Rat
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
ZAK
Background:
This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
35kDa/51kDa/91kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human ZAK (NP_598407.1).
ObservedMW:
105kDa
Purification method:
Affinity purification
Target Synonym:
MAP3K20;AZK;MLK7;MLT;MLTK;MLTKalpha;MLTKbeta;MRK;SFMMP;ZAK;mlklak;pk
UNIProt ID:
Q9NYL2