LMNA Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-40252-20uL | 20uL | £120.00 |
Quantity:
| E-AB-40252-60uL | 60uL | £160.00 |
Quantity:
| E-AB-40252-120uL | 120uL | £230.00 |
Quantity:
| E-AB-40252-200uL | 200uL | £331.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
LMNA
Background:
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Calculated MW:
63,64,65,69,71,74 kDa
Concentration:
2 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:1000
Immunogen:
Recombinant Human Prelamin-A/C protein
ObservedMW:
71,74 kDa
Purification method:
Affinity Purification
Target Synonym:
70 kDa lamin;Cardiomyopathy dilated 1A (autosomal dominant);CDCD1;CDDC;CMD1A;CMT2B1;EMD2;FPL;FPLD;FPLD2;HGPS;IDC;Lamin A;Lamin A/C;Lamin A/C like 1;Lamin;Lamin C;Lamin-A/C;LDP1;LFP;LGMD1B;Limb girdle muscular dystrophy 1B (autosomal dominant);LMN 1;LMN A;LMN C;LMN1;LMNA;LMNA;LMNC;LMNL1;Prelamin A/C;PRO1;Renal carcinoma antigen NY REN 32;Renal carcinoma antigen NY-REN-32;Renal carcinoma antigen NYREN32
UNIProt ID:
P02545