LEPR Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-60812-60uL | 60uL | £210.00 |
Quantity:
| E-AB-60812-120uL | 120uL | £291.00 |
Quantity:
| E-AB-60812-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
LEPR
Background:
The protein encoded by this gene belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID:54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID:9207021).
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
96kDa/102kDa/103kDa/109kDa/132kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:1000
Immunogen:
A synthetic peptide of human LEPR
ObservedMW:
113kDa
Purification method:
Affinity purification
Target Synonym:
CD295;LEP-R;LEPRD;OB-R;OBR;LEPR
UNIProt ID:
P48357