LDLR Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-70239-60uL | 60uL | £184.00 |
Quantity:
| E-AB-70239-120uL | 120uL | £251.00 |
Quantity:
| E-AB-70239-200uL | 200uL | £351.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
LDLR
Background:
LDLR (low density lipoprotein receptor) is a member of the LDL receptor gene family and is involved in receptor-mediated endocytosis of specific ligands. The LDLR is a cell surface glycoprotein that scavenges LDL from the blood and regulates plasma LDL cholesterol. The cytoplasmic domain of the LDL receptor is necessary for the receptor to cluster in coated pits,which promotes the rapid endocytosis of bound LDL. The protein is highly glycosylated through N- and O-linkages and thus migrates at 100 to 160 kDa bands on SDS-PAGE.
Buffer:
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:200-1:1000
Immunogen:
KLH conjugated Synthetic peptide corresponding to LDL Receptor
Purification method:
Affinity purification
Target Synonym:
FH;FHC;LDL R;LDL receptor;LDLCQ2;Ldlr;LDLR;Low Density Lipoprotein Receptor;Low density lipoprotein receptor class A domain containing protein 3;Low density lipoprotein receptor familial hypercholesterolemia;Low-density lipoprotein receptor
UNIProt ID:
P01130,P35951,P35952
References
- https://static.frontiersin.org/articles/10.3389/fonc.2022.903033/full