Lamin B1 Polyclonal Antibody

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Elabscience
Product Code: E-AB-40257
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-40257-30uL30uL£125.00
Quantity:
E-AB-40257-60uL60uL£160.00
Quantity:
E-AB-40257-120uL120uL£196.00
Quantity:
E-AB-40257-200uL200uL£331.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western Blot analysis of HepG2 cell using Lamin B1 Polyclonal Antibody at dilution of 1:1000
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Western Blot analysis of Rat heart and Rat brain using Lamin B1 Polyclonal Antibody at dilution of 1:1000
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Western Blot analysis of Mouse kidney, Mouse lung and Mouse spleen using Lamin B1 Polyclonal Antibody at dilution of 1:1000
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Immunohistochemistry of paraffin-embedded Human liver tissue using Lamin-B1 Polyclonal Antibody at dilution of 1:600(?400)
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Immunohistochemistry of paraffin-embedded Human breast cancer using Lamin B1 Polyclonal Antibody at dilution of 1:100
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Immunohistochemistry of paraffin-embedded Mouse liver using Lamin B1 Polyclonal Antibody at dilution of 1:100
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Immunohistochemistry of paraffin-embedded Human uterus using Lamin B1 Polyclonal Antibody at dilution of 1:100(Elabscience Product Detected by Lifespan).
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Immunofluorescence analysis of HepG2 cells using Lamin B1 Polyclonal Antibody at dilution of 1:200
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Western Blot analysis of HepG2 cell using Lamin B1 Polyclonal Antibody at dilution of 1:1000
Western Blot analysis of Rat heart and Rat brain using Lamin B1 Polyclonal Antibody at dilution of 1:1000
Western Blot analysis of Mouse kidney, Mouse lung and Mouse spleen using Lamin B1 Polyclonal Antibody at dilution of 1:1000
Immunohistochemistry of paraffin-embedded Human liver tissue using Lamin-B1 Polyclonal Antibody at dilution of 1:600(?400)
Immunohistochemistry of paraffin-embedded Human breast cancer using Lamin B1 Polyclonal Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded Mouse liver using Lamin B1 Polyclonal Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded Human uterus using Lamin B1 Polyclonal Antibody at dilution of 1:100(Elabscience Product Detected by Lifespan).
Immunofluorescence analysis of HepG2 cells using Lamin B1 Polyclonal Antibody at dilution of 1:200

Documents

Further Information

Abbreviation:
Lamin B1
Background:
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD).
Buffer:
PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Calculated MW:
67 kDa
Concentration:
0.3mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:250-1:500, IHC 1:200-1:600
Immunogen:
Recombinant Rat Lamin-B1 protein expressed by E.coli
ObservedMW:
72 kDa
Purification method:
Antigen Affinity Purification
Target Synonym:
ADLD;lamin B1;Lamin-B1;LMN;LMN2;LMNB;Lmnb1;LMNB1;MGC111419;OTTHUMP00000159218
UNIProt ID:
P70615

References

  • https://link.springer.com/article/10.1007/s12035-022-02923-2