KCNQ1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-60659-60uL | 60uL | £210.00 |
Quantity:
| E-AB-60659-120uL | 120uL | £291.00 |
Quantity:
| E-AB-60659-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
KCNQ1
Background:
This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation. This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others. This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS), and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS. Alternatively spliced transcript variants have been found for this gene.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
61kDa/74kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human KCNQ1 (NP_861463.1).
ObservedMW:
70kDa
Purification method:
Affinity purification
Target Synonym:
KCNQ1;ATFB1;ATFB3;JLNS1;KCNA8;KCNA9;KVLQT1;Kv1.9;Kv7.1;LQT;LQT1;RWS;SQT2;WRS
UNIProt ID:
P51787