JNK2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-40228-20uL | 20uL | £120.00 |
Quantity:
| E-AB-40228-60uL | 60uL | £160.00 |
Quantity:
| E-AB-40228-120uL | 120uL | £230.00 |
Quantity:
| E-AB-40228-200uL | 200uL | £331.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Mouse
- Rat
Application: Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
JNK2
Background:
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.
Buffer:
PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Concentration:
2 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant Rat Mitogen-activated protein kinase 9 protien
Purification method:
Affinity purification
Target Synonym:
c Jun kinase 2;C Jun N terminal kinase 2;c-Jun N-terminal kinase 2;JNK 55;JNK-55;JNK2 alpha;JNK2;JNK2 beta;JNK2A;JNK2alpha;JNK2B;JNK2BETA;Jun kinase;MAP kinase 9;MAPK 9;Mapk9;Mitogen activated protein kinase 9;Mitogen-activated protein kinase 9;MK09_HUMAN;P54a;p54aSAPK;PRKM9;Protein kinase; mitogen-activated; 9;SAPK alpha;SAPK;SAPK1a;Stress activated protein kinase 1a;Stress-activated protein kinase JNK2
UNIProt ID:
P49186