ITGAV Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-70152-60uL | 60uL | £184.00 |
Quantity:
| E-AB-70152-120uL | 120uL | £251.00 |
Quantity:
| E-AB-70152-200uL | 200uL | £351.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
ITGAV
Background:
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.
Buffer:
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Calculated MW:
116kDa
Concentration:
0.76 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:1000
Immunogen:
KLH conjugated Synthetic peptide corresponding to Mouse Integrin alpha-V
ObservedMW:
130kDa
Purification method:
Affinity purification
Target Synonym:
antigen identified by monoclonal L230;CD 51;CD51;DKFZp686A08142;Integrin alpha five;integrin alpha V beta 3;Integrin alpha-5;integrin alpha-V;Integrin alpha-V light chain;integrin alphaVbeta3;integrin;alpha V (vitronectin receptor;alpha polypeptide;antigen CD51);ITAV;ITGAV;MSK 8;Msk8;Vitronectin receptor subunit alpha;VNRA;VTNR
UNIProt ID:
P06756,P43406