IL4 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-62102-60uL | 60uL | £210.00 |
Quantity:
| E-AB-62102-120uL | 120uL | £291.00 |
Quantity:
| E-AB-62102-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
IL4
Background:
The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:100
Immunogen:
Recombinant fusion protein of human IL4 (NP_000580.1).
Purification method:
Affinity purification
Target Synonym:
IL4;BCGF-1;BCGF1;BSF-1;BSF1;IL-4
UNIProt ID:
P05112
References
- https://www.sciencedirect.com/science/article/pii/S0378874121009168