IKB alpha Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-63487-60uL | 60uL | £210.00 |
Quantity:
| E-AB-63487-120uL | 120uL | £291.00 |
Quantity:
| E-AB-63487-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
IKB alpha
Background:
This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200 IF 1:20-1:100
Immunogen:
Recombinant fusion protein of human IKB alpha (NP_065390.1).
Purification method:
Affinity purification
Target Synonym:
IKBA;MAD-3;NFKBI;IKB alpha;NFKBIA;EDAID2
UNIProt ID:
P25963