HAX1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-61005-60uL | 60uL | £210.00 |
Quantity:
| E-AB-61005-120uL | 120uL | £291.00 |
Quantity:
| E-AB-61005-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunofluorescence (IF)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
HAX1
Background:
The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Calculated MW:
14kDa/21kDa/26kDa/28kDa/31kDa/32kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000,IF 1:10-1:100
Immunogen:
Recombinant fusion protein of human HAX1
ObservedMW:
36kDa
Purification method:
Affinity purification
Target Synonym:
HAX1;HCLSBP1;HS1BP1;SCN3
UNIProt ID:
O00165