GSK3 beta Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-70043-60uL | 60uL | £184.00 |
Quantity:
| E-AB-70043-120uL | 120uL | £251.00 |
Quantity:
| E-AB-70043-200uL | 200uL | £351.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
GSK3 beta
Background:
The protein encoded by this gene is a serine-threonine kinase belonging to the glycogen synthase kinase subfamily. It is a negative regulator of glucose homeostasis and is involved in energy metabolism, inflammation, ER-stress, mitochondrial dysfunction, and apoptotic pathways. Defects in this gene have been associated with Parkinson disease and Alzheimer disease.
Buffer:
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Calculated MW:
47kDa
Concentration:
2 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:300-1:800, IF 1:200-1:500
Immunogen:
KLH conjugated Synthetic peptide corresponding to Mouse GSK3β
ObservedMW:
47kDa
Purification method:
Affinity purification
Target Synonym:
Glycogen Synthase Kinase 3 Beta;Glycogen synthase kinase-3 beta;GSK 3 beta;GSK-3 beta;GSK3B;GSK3B;GSK3beta isoform;Serine/threonine-protein kinase GSK3B
UNIProt ID:
P49841,Q9WV60,P18266
References
- https://www.sciencedirect.com/science/article/pii/S0300483X22001044