GLUD1 Polyclonal Antibody

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Elabscience
Product Code: E-AB-62764
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-62764-60uL60uL£210.00
Quantity:
E-AB-62764-120uL120uL£291.00
Quantity:
E-AB-62764-200uL200uL£431.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunohistochemistry of paraffin-embedded Human liver cancer using GLUD1 Polyclonal Antibody at dilution of 1:100 (40x lens).
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Immunohistochemistry of paraffin-embedded Human colon carcinoma using GLUD1 Polyclonal Antibody at dilution of 1:100 (40x lens).
3 / 8
Immunohistochemistry of paraffin-embedded Human esophagus using GLUD1 Polyclonal Antibody at dilution of 1:100 (40x lens).
4 / 8
Immunofluorescence analysis of C6 cells using GLUD1 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
5 / 8
Immunofluorescence analysis of NIH-3T3 cells using GLUD1 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
6 / 8
Immunofluorescence analysis of C6 cells using GLUD1 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
7 / 8
Immunofluorescence analysis of NIH-3T3 cells using GLUD1 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
8 / 8
Immunofluorescence analysis of U-2 OS cells using GLUD1 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
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Immunohistochemistry of paraffin-embedded Human liver cancer using GLUD1 Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Human colon carcinoma using GLUD1 Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Human esophagus using GLUD1 Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunofluorescence analysis of C6 cells using GLUD1 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of NIH-3T3 cells using GLUD1 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of C6 cells using GLUD1 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of NIH-3T3 cells using GLUD1 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Immunofluorescence analysis of U-2 OS cells using GLUD1 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.

Documents

Further Information

Abbreviation:
GLUD1
Background:
This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:100-1:200 IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human GLUD1 (NP_005262.1).
Purification method:
Affinity purification
Target Synonym:
GLUD1;GDH;GDH1;GLUD
UNIProt ID:
P00367