Glucocorticoid Receptor Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-70157-60uL | 60uL | £184.00 |
Quantity:
| E-AB-70157-120uL | 120uL | £251.00 |
Quantity:
| E-AB-70157-200uL | 200uL | £351.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
Glucocorticoid Receptor
Background:
This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms.
Buffer:
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Calculated MW:
91kDa
Concentration:
1.3 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:1000, IHC 1:500-1:1000
Immunogen:
Recombinant proteincorresponding to Mouse Glucocorticoid receptor
ObservedMW:
91kDa
Purification method:
Affinity purification
Target Synonym:
GCCR;GCR;GCR;GCRST;glucocorticoid nuclear receptor variant 1;Glucocorticoid receptor;GR;GRL;Grl1;nr3c1;Nuclear receptor subfamily 3 group C member 1;nuclear receptor subfamily 3;group C;member 1 (glucocorticoid receptor)
UNIProt ID:
P04150,P06536,P06537