GAD2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-60117-60uL | 60uL | £210.00 |
Quantity:
| E-AB-60117-120uL | 120uL | £291.00 |
Quantity:
| E-AB-60117-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunofluorescence (IF)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
GAD2
Background:
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
65kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000,IF 1:10-1:100
Immunogen:
Recombinant fusion protein of human GAD2
ObservedMW:
60KDa
Purification method:
Affinity purification
Target Synonym:
GAD2;GAD65
UNIProt ID:
Q05329
References
- https://www.sciencedirect.com/science/article/pii/S0361923018308645