FLNB Polyclonal Antibody

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Elabscience
Product Code: E-AB-62747
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-62747-60uL60uL£210.00
Quantity:
E-AB-62747-120uL120uL£291.00
Quantity:
E-AB-62747-200uL200uL£431.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunohistochemistry of paraffin-embedded Human liver damage using FLNB Polyclonal Antibody at dilution of 1:100 (40x lens).
2 / 3
Immunofluorescence analysis of HUVEC cells using FLNB Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
3 / 3
Immunofluorescence analysis of PC-12 cells using FLNB Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
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Immunohistochemistry of paraffin-embedded Human liver damage using FLNB Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunofluorescence analysis of HUVEC cells using FLNB Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Immunofluorescence analysis of PC-12 cells using FLNB Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.

Documents

Further Information

Abbreviation:
FLNB
Background:
This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3; boomerang dysplasia; autosomal dominant Larsen syndrome; and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:100 IF 1:20-1:100
Immunogen:
Recombinant fusion protein of human FLNB (NP_001157789.1).
Purification method:
Affinity purification
Target Synonym:
FLNB;ABP-278;ABP-280;AOI;FH1;FLN-B;FLN1L;LRS1;SCT;TABP;TAP;filamin-B
UNIProt ID:
O75369