FGF2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-60031-60uL | 60uL | £210.00 |
Quantity:
| E-AB-60031-120uL | 120uL | £291.00 |
Quantity:
| E-AB-60031-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
FGF2
Background:
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
17kDa/21kDa/22kDa/30kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human FGF2 (NP_001997.5).
ObservedMW:
20kDa
Purification method:
Affinity purification
Target Synonym:
BFGF;FGF-2;FGFB;HBGF-2;Basic FGF;FGF2
UNIProt ID:
P09038
References
- https://onlinelibrary.wiley.com/doi/abs/10.1111/cpr.13345