FBXW11 Polyclonal Antibody

Elabscience
Product Code: E-AB-62391
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-62391-60uL60uL£210.00
Quantity:
E-AB-62391-120uL120uL£291.00
Quantity:
E-AB-62391-200uL200uL£431.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunofluorescence (IF)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

1 / 2
Immunofluorescence analysis of A-431 cells using FBXW11 Polyclonal Antibody at dilution of 1:200 (40x lens). Blue: DAPI for nuclear staining.
2 / 2
Immunofluorescence analysis of PC-12 cells using FBXW11 Polyclonal antibody at dilution of 1:200 (40x lens). Blue: DAPI for nuclear staining.

Immunofluorescence analysis of A-431 cells using FBXW11 Polyclonal Antibody at dilution of 1:200 (40x lens). Blue: DAPI for nuclear staining.
Immunofluorescence analysis of PC-12 cells using FBXW11 Polyclonal antibody at dilution of 1:200 (40x lens). Blue: DAPI for nuclear staining.

Documents

Further Information

Abbreviation:
FBXW11
Background:
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons.
Buffer:
PBS with 0.01% thiomersal,50% glycerol,pH7.3.
Calculated MW:
58kDa/60kDa/62kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000,IF 1:50-1:100
Immunogen:
Recombinant fusion protein of human FBXW11
ObservedMW:
62KDa
Purification method:
Affinity purification
Target Synonym:
FBXW11;BTRC2;BTRCP2;FBW1B;FBXW1B;Fbw11;Hos
UNIProt ID:
Q9UKB1