EZH2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-70131-60uL | 60uL | £184.00 |
Quantity:
| E-AB-70131-120uL | 120uL | £251.00 |
Quantity:
| E-AB-70131-200uL | 200uL | £351.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
EZH2
Background:
EZH2 (enhancer of zeste homologue 2,also known as KMT6) is a member of Polycomb group (PcG) family and encodes a histone methyl transferase that has an essential role in promoting histone H3 lysine 27 trimethylation (H3K27me3) and epigenetic gene silencing. EZH2 is important for cell proliferation and inhibition of cell differentiation,and is implicated in cancer progression. Overexpression of EZH2 is a marker of advanced and metastatic disease in many solid tumors,including prostate and breast cancer. This antibody detected EZH2 protein as a single band with a molecular weight (MW) of 91-100 kDa in multiple cell lines. The phosphorylation may result in the higher molecular weight (calculated MW as 80-86 kDa). (20935635,21367748)
Buffer:
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Calculated MW:
80-100kDa
Concentration:
0.54 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
KLH conjugated Synthetic peptide corresponding to Mouse EZH2
ObservedMW:
80kDa
Purification method:
Affinity purification
Target Synonym:
Enhancer of zeste 2;enhancer of zeste 2 polycomb repressive complex 2 subunit;Enhancer of zeste homolog 2 (Drosophila);Enhancer of zeste homolog 2;Enhancer of zeste;Drosophila;homolog 2;ENX 1;Enx 1h;ENX-1;ENX1;Enx1h;EZH 2;EZH1;EZH2;EZH2;EZH2b;Histone-lysine N-methyltransferase EZH2;KMT 6;KMT6;KMT6A;Lysine N-methyltransferase 6;MGC9169;WVS;WVS2
UNIProt ID:
Q15910,Q61188