ERCC2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-61805-60uL | 60uL | £210.00 |
Quantity:
| E-AB-61805-120uL | 120uL | £291.00 |
Quantity:
| E-AB-61805-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Rat
Application: Immunofluorescence (IF)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
ERCC2
Background:
The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
IF 1:50-1:100
Immunogen:
Recombinant fusion protein of human ERCC2 (NP_001124339.1).
Purification method:
Affinity purification
Target Synonym:
ERCC2;COFS2;EM9;TFIIH;TTD;TTD1;XPD
UNIProt ID:
P18074