(KO Validated) HuR / ELAVL1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-65532-60uL | 60uL | £224.00 |
Quantity:
| E-AB-65532-120uL | 120uL | £317.00 |
Quantity:
| E-AB-65532-200uL | 200uL | £465.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Applications:
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
HuR / ELAVL1
Background:
The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
36kDa/38kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:1000 IHC 1:50-1:200 IF 1:50-1:200
Immunogen:
A synthetic peptide of human HuR / ELAVL1 (NP_001410.2).
ObservedMW:
36kDa
Purification method:
Affinity purification
Target Synonym:
ELAV1;HUR;Hua;MelG;HuR / ELAVL1;ELAVL1
UNIProt ID:
Q15717