EIF2S1 Polyclonal Antibody
Code | Size | Price |
---|
E-AB-62069-60uL | 60uL | £210.00 |
Quantity:
E-AB-62069-120uL | 120uL | £291.00 |
Quantity:
E-AB-62069-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Images
Further Information
Abbreviation:
EIF2S1
Background:
The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010]
Buffer:
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Calculated MW:
36kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:1000
Immunogen:
Recombinant fusion protein of human EIF2S1
ObservedMW:
38KDa
Purification method:
Affinity purification
Target Synonym:
EIF-2;EIF-2A;EIF-2alpha;EIF2;EIF2A;EIF2S1
UNIProt ID:
P05198