DMAP1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-62489-60uL | 60uL | £210.00 |
Quantity:
| E-AB-62489-120uL | 120uL | £291.00 |
Quantity:
| E-AB-62489-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
DMAP1
Background:
This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
52kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:4000
Immunogen:
Recombinant fusion protein of human DMAP1 (NP_061973.1).
ObservedMW:
60kDa
Purification method:
Affinity purification
Target Synonym:
DMAP1;DNMAP1;DNMTAP1;EAF2;MEAF2;SWC4
UNIProt ID:
Q9NPF5