DKC1 Polyclonal Antibody

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Elabscience
Product Code: E-AB-64375
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-64375-60uL60uL£210.00
Quantity:
E-AB-64375-120uL120uL£291.00
Quantity:
E-AB-64375-200uL200uL£431.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Immunofluorescence analysis of NIH-3T3 cells using DKC1 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
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Immunofluorescence analysis of NIH-3T3 cells using DKC1 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.

Documents

Further Information

Abbreviation:
DKC1
Background:
This gene functions in two distinct complexes. It plays an active role in telomerase stabilization and maintenance, as well as recognition of snoRNAs containing H/ACA sequences which provides stability during biogenesis and assembly into H/ACA small nucleolar RNA ribonucleoproteins (snoRNPs). This gene is highly conserved and widely expressed, and may play additional roles in nucleo-cytoplasmic shuttling, DNA damage response, and cell adhesion. Mutations have been associated with X-linked dyskeratosis congenita. Alternative splicing results in multiple transcript variants.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:100 IF 1:50-1:100
Immunogen:
Recombinant fusion protein of human DKC1 (NP_001354.1).
Purification method:
Affinity purification
Target Synonym:
DKC1;CBF5;DKC;DKCX;NAP57;NOLA4;XAP101
UNIProt ID:
O60832