CYCS Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-70033-60uL | 60uL | £184.00 |
Quantity:
| E-AB-70033-120uL | 120uL | £251.00 |
Quantity:
| E-AB-70033-200uL | 200uL | £351.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
CYCS
Background:
Cytochrome c is a 12-15 kDa electron transporting protein located in the inner mitochondrial membrane. Upon apoptotic stimulation,cytochrome c can be released from mitochondria into cytoplasm,resulting in caspase-3 activation and apoptosis. Measurement of cytochrome c release from the mitochondria is useful for detection of the onset of apoptosis in cells. In addition,cytochrome c can also leave cells and be detectable in extra-cellular medium of apoptotic cells and serum of cancer patients. The level of serum cytochrome c may serve as a prognostic maker during cancer therapy.
Buffer:
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Calculated MW:
12kDa
Concentration:
1.5 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1:500-1:1000, IF 1:200-1:800
Immunogen:
KLH conjugated Synthetic peptide corresponding to Mouse Cytochrome c
ObservedMW:
12kDa
Purification method:
Affinity purification
Target Synonym:
Cytochrome C; Somatic;CYC;Cytochrome C;THC4;HCS.
UNIProt ID:
P99999,P62898,P62897
References
- https://link.springer.com/article/10.1007/s11696-019-00894-8