CYBB Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-70273-60uL | 60uL | £184.00 |
Quantity:
| E-AB-70273-120uL | 120uL | £251.00 |
Quantity:
| E-AB-70273-200uL | 200uL | £351.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Mouse
- Rat
Application: Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
CYBB
Background:
Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles.
Buffer:
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Concentration:
270 ug/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:200-1:1000
Immunogen:
Recombinant protein corresponding to Mouse NOX2
Purification method:
Affinity purification
Target Synonym:
AMCBX2;CGD;CGD91-phox;CY24B;CYBB;Cytochrome b 245;beta polypeptide;Cytochrome b(558) beta chain;Cytochrome b(558) subunit beta;Cytochrome b-245 heavy chain;Cytochrome b558 subunit beta;GP91 PHOX;gp91-1;gp91-phox;GP91PHOX;Heme-binding membrane glycoprotein gp91phox;NADPH oxidase 2;Neutrophil cytochrome b 91 kDa polypeptide;NOX2;p22 phagocyte B-cytochrome;P91 PHOX;p91-PHOX;Superoxide-generating NADPH oxidase heavy chain subunit
UNIProt ID:
Q61093