COL18A1 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-70197-60uL | 60uL | £184.00 |
Quantity:
| E-AB-70197-120uL | 120uL | £251.00 |
Quantity:
| E-AB-70197-200uL | 200uL | £351.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
COL18A1
Background:
This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. The proteolytically produced C-terminal fragment of type XVIII collagen is endostatin, a potent antiangiogenic protein. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Buffer:
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Concentration:
1.1 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:300-1:1000
Immunogen:
KLH conjugated Synthetic peptide corresponding to Mouse Endostatin
Purification method:
Affinity purification
Target Synonym:
Antiangiogenic agent;COIA1;Col18a1;Collagen alpha 1(XVIII) chain;Collagen type XVIII alpha 1;Endostatin;KNO;KNO1;KS;Multi functional protein MFP
UNIProt ID:
P39060,P39061