CNOT8 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-62996-60uL | 60uL | £210.00 |
Quantity:
| E-AB-62996-120uL | 120uL | £291.00 |
Quantity:
| E-AB-62996-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
CNOT8
Background:
Has 3'-5' poly(A exoribonuclease activity for synthetic poly(A RNA substrate. Its function seems to be partially redundant with that of CNOT7. Catalytic component of the CCR4-NOT complex which is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity.
Buffer:
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Calculated MW:
21kDa/27kDa/33kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human CNOT8
ObservedMW:
34kDa
Purification method:
Affinity purification
Target Synonym:
CNOT8;CAF1;CALIF;Caf1b;POP2;hCAF1
UNIProt ID:
Q9UFF9