CHOP Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-70087-60uL | 60uL | £184.00 |
Quantity:
| E-AB-70087-120uL | 120uL | £251.00 |
Quantity:
| E-AB-70087-200uL | 200uL | £351.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
CHOP
Background:
CHOP,also known as GADD153 or DDIT3,is a highly conserved gene in both the structural and regulatory regions to hamster gene.Imposed by unfolded and malfolded proteins,CHOP is significantly induced by ER stress,deficiency of CHOP prevents cell from ER stress. CHOP is considered a proapoptotic marker of ER stress dependent cell death. CHOP acts as a dominant-negative inhibitor of the transcription factor C/EBP and LAP by forming a heterodimer. It may play an important role in the malignant transformation of nevus to melanoma.
Buffer:
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:100-500
Immunogen:
KLH conjugated Synthetic peptide corresponding to Mouse CHOP
Purification method:
Affinity purification
Target Synonym:
C/EBP homologous protein;C/EBP Homology Protein;C/EBP zeta;C/EBP-homologous protein 10;C/EBP-homologous protein;CCAAT/enhancer binding protein homologous protein;CEBPZ;CHOP 10;CHOP;CHOP-10;CHOP10;DDIT 3;DDIT-3;Ddit3;DDIT3;DNA Damage Inducible Transcript 3;DNA damage-inducible transcript 3 protein;GADD 153;GADD153;Growth Arrest and DNA Damage Inducible Protein 153;Growth arrest and DNA damage inducible protein GADD153;Growth arrest and DNA damage-inducible protein GADD153;MGC4154
UNIProt ID:
P35638,P35639,Q62857