CHD3 Polyclonal Antibody
Code | Size | Price |
---|
E-AB-63718-60uL | 60uL | £210.00 |
Quantity:
E-AB-63718-120uL | 120uL | £291.00 |
Quantity:
E-AB-63718-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Images
Further Information
Abbreviation:
CHD3
Background:
This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
222kDa/226kDa/233kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:200-1:1000
Immunogen:
A synthetic peptide of human CHD3 (NP_001005273.1).
ObservedMW:
280kDa
Purification method:
Affinity purification
Target Synonym:
CHD3;Mi-2a;Mi2-ALPHA;ZFH
UNIProt ID:
Q12873