CFH Polyclonal Antibody
Code | Size | Price |
---|
E-AB-60653-60uL | 60uL | £210.00 |
Quantity:
E-AB-60653-120uL | 120uL | £291.00 |
Quantity:
E-AB-60653-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Immunohistochemistry (IHC)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Images
Further Information
Abbreviation:
CFH
Background:
This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short consensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:50-1:200
Immunogen:
Recombinant fusion protein of human CFH (NP_001014975.1).
Purification method:
Affinity purification
Target Synonym:
CFH;AHUS1;AMBP1;ARMD4;ARMS1;CFHL3;FH;FHL1;HF;HF1;HF2;HUS
UNIProt ID:
P08603