CD54 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-70046-60uL | 60uL | £184.00 |
Quantity:
| E-AB-70046-120uL | 120uL | £251.00 |
Quantity:
| E-AB-70046-200uL | 200uL | £351.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
CD54
Background:
ICAM-1 (CD54) is a 90-kDa transmembrane glycoprotein of the immunoglobulin superfamily and is critical for the firm attachment and transmigration of leukocytes out of blood vessels and into tissues . ICAM-1 is expressed by several cell types,typically on endothelial cells and cells of the immune system,and its expression can be up-regulated by various stimuli,including TNF-α,INF-γ,IL-1 and thrombin . It is a ligand for LFA-1 and Mac-1,serves as a receptor for rhinovirus,and is one of several receptors used by Plasmodium falciparum .
Buffer:
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Calculated MW:
58kDa
Concentration:
0.84 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:1000-1:3000, IHC 1:500-1:1000, IF 1:200-1:800
Immunogen:
KLH conjugated Synthetic peptide corresponding to Mouse ICAM-1
ObservedMW:
58kDa
Purification method:
Affinity purification
Target Synonym:
Antigen identified by monoclonal BB2;BB 2;BB2;CD 54;CD_antigen=CD54;CD54;Cell surface glycoprotein P3.58;Human rhinovirus receptor;ICAM 1;ICAM-1;ICAM1;ICAM1;intercellular adhesion molecule 1 (CD54);human rhinovirus receptor;Intercellular adhesion molecule 1;Major group rhinovirus receptor;MALA 2;MALA2;MyD 10;MyD10;P3.58;Surface antigen of activated B cells;BB2
UNIProt ID:
P05362,Q00238,P13597
References
- https://www.ahajournals.org/doi/abs/10.1161/CIRCULATIONAHA.122.058794
- https://pubs.acs.org/doi/abs/10.1021/acsami.9b22214