CD284 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-70375-60uL | 60uL | £184.00 |
Quantity:
| E-AB-70375-120uL | 120uL | £251.00 |
Quantity:
| E-AB-70375-200uL | 200uL | £351.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Immunohistochemistry (IHC)
- Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
CD284
Background:
TLR4,also named as CD284,belongs to the Toll-like receptor family. TLR4 cooperates with LY96 and CD14 to mediates the innate immune response to bacterial lipopolysaccharide (LPS). TLR4 acts via MYD88,TIRAP and TRAF6,leading to NF-kappa-B activation,cytokine secretion and the inflammatory response. Three alternatively spliced transcript variants that encode different protein isoforms have been described.
Buffer:
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Calculated MW:
95kDa
Concentration:
0.9 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000, IHC 1::500-1:2000
Immunogen:
KLH conjugated Synthetic peptide corresponding to Mouse TLR4.
ObservedMW:
95kDa
Purification method:
Affinity purification
Target Synonym:
ARMD10;CD284;CD284 antigen;Homolog of Drosophila toll;hToll;TLR 4;TLR4;TLR4;TOLL;Toll like receptor 4;Toll-like receptor 4
UNIProt ID:
O00206,Q9QUK6,Q9QX05
References
- https://www.sciencedirect.com/science/article/pii/S0024320521008626
- https://academic.oup.com/jpp/article-abstract/73/4/473/6118677