Elabscience

ANPEP Polyclonal Antibody

Product Code:
 
E-AB-61048
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
  • Rat
Application:
 
Western Blot (WB)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Western blot analysis of extracts of various cell lines using ANPEP Polyclonal Antibody at dilution of 1:1000.
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Western blot analysis of extracts of various cell lines using ANPEP Polyclonal Antibody at dilution of 1:1000.

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E-AB-61048-60uL60uL£210.00
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E-AB-61048-120uL120uL£291.00
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E-AB-61048-200uL200uL£431.00
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This product comes from: China.
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Further Information

Abbreviation:
ANPEP
Background:
Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
109kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human ANPEP (NP_001141.2).
ObservedMW:
180kDa
Purification method:
Affinity purification
Target Synonym:
ANPEP;APN;CD13;GP150;LAP1;P150;PEPN
UNIProt ID:
P15144

Documents