Elabscience

CCR5 Polyclonal Antibody

Product Code:
 
E-AB-70361
Product Group:
 
Primary Antibodies
Supplier:
 
Elabscience
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Mouse
  • Rat
Application:
 
Immunohistochemistry (IHC)
Shipping:
 
Ice packs
Storage:
 
Store at -20°C. Avoid freeze / thaw cycles.
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Immunohistochemistry analysis of paraffin-embedded rat spleen using CCR5 Polyclonal Antibody at dilution of 1:300.
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Immunohistochemistry analysis of paraffin-embedded rat spleen using CCR5 Polyclonal Antibody at dilution of 1:300.

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E-AB-70361-60uL60uL£184.00
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E-AB-70361-200uL200uL£351.00
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Further Information

Abbreviation:
CCR5
Background:
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation.
Buffer:
PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4
Concentration:
0.55 mg/mL
Conjugation:
Unconjugated
Dilution:
IHC 1:200-1:800
Immunogen:
KLH conjugated Synthetic peptide corresponding to Mouse CCR5
Purification method:
Affinity purification
Target Synonym:
AM4 7;C C chemokine receptor type 5;C C CKR 5;C-C chemokine receptor type 5;C-C CKR-5;C-C motif chemokine receptor 5 A159A;CC Chemokine Receptor 5;CC Chemokine Receptor Type 5;CC CKR 5;CC-CKR-5;CCCKR 5;CCCKR5;CCR 5;CCR-5;CCR5;CCR5 chemokine (C C motif) receptor 5;CCR5;CD 195;CD195;CD195 Antigen;Chemokine C C motif receptor 5;Chemokine receptor CCR5;CHEMR13;CKR 5;CKR5;CMKBR 5;CMKBR5;FLJ78003;HIV 1 Fusion Coreceptor;HIV-1 fusion coreceptor;HIV1 fusion coreceptor;IDDM22;MIP-1 alpha receptor
UNIProt ID:
P51682,O08556

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