Caspase-2 Polyclonal Antibody
| Code | Size | Price |
|---|
| E-AB-61085-60uL | 60uL | £210.00 |
Quantity:
| E-AB-61085-120uL | 120uL | £291.00 |
Quantity:
| E-AB-61085-200uL | 200uL | £431.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Application: Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
Further Information
Abbreviation:
Caspase-2
Background:
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Buffer:
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Calculated MW:
10kDa/34kDa/50kDa
Concentration:
1 mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000
Immunogen:
Recombinant fusion protein of human Caspase-2
ObservedMW:
48KDa
Purification method:
Affinity purification
Target Synonym:
CASP2;CASP-2;ICH1;NEDD-2;NEDD2;PPP1R57;caspase-2
UNIProt ID:
P42575