CAMLG Polyclonal Antibody

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Elabscience
Product Code: E-AB-64807
Product Group: Primary Antibodies
Supplier: Elabscience
CodeSizePrice
E-AB-64807-60uL60uL£210.00
Quantity:
E-AB-64807-120uL120uL£291.00
Quantity:
E-AB-64807-200uL200uL£431.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Shipping:
Ice packs
Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Images

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Western blot analysis of extracts of various cell lines using CAMLG Polyclonal Antibody at dilution of 1:3000.
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Immunohistochemistry of paraffin-embedded Human breast cancer using CAMLG Polyclonal Antibody at dilution of 1:100 (40x lens).
3 / 7
Immunohistochemistry of paraffin-embedded Human stomach using CAMLG Polyclonal Antibody at dilution of 1:100 (40x lens).
4 / 7
Immunohistochemistry of paraffin-embedded Mouse lung using CAMLG Polyclonal Antibody at dilution of 1:100 (40x lens).
5 / 7
Immunohistochemistry of paraffin-embedded Mouse liver using CAMLG Polyclonal Antibody at dilution of 1:100 (40x lens).
6 / 7
Immunofluorescence analysis of NIH-3T3 cells using CAMLG Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
7 / 7
Immunofluorescence analysis of U-2 OS cells using CAMLG Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
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Western blot analysis of extracts of various cell lines using CAMLG Polyclonal Antibody at dilution of 1:3000.
Immunohistochemistry of paraffin-embedded Human breast cancer using CAMLG Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Human stomach using CAMLG Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Mouse lung using CAMLG Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Mouse liver using CAMLG Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunofluorescence analysis of NIH-3T3 cells using CAMLG Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.
Immunofluorescence analysis of U-2 OS cells using CAMLG Polyclonal Antibody at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.

Documents

Further Information

Abbreviation:
CAMLG
Background:
The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.
Buffer:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Calculated MW:
32kDa
Concentration:
1mg/mL
Conjugation:
Unconjugated
Dilution:
WB 1:500-1:2000 IHC 1:50-1:100 IF 1:50-1:200
Immunogen:
Recombinant fusion protein of human CAMLG (NP_001736.1).
ObservedMW:
38kDa
Purification method:
Affinity purification
Target Synonym:
CAMLG;CAML;GET2
UNIProt ID:
P49069